Baja California: Ensenada, Valle de Guadalupe & Mission Route
Ninety minutes south of San Diego across the US-Mexico border, Baja California's Valle de Guadalupe has become Mexico's premier wine region — 150 boutique wineries in a Mediterranean microclimate that produces the best nebbiolo and grenache in the Americas. The valley's outdoor restaurant scene (Finca Altozano, Corazon de Tierra, Animalon) has made it a destination for chefs from Mexico City and Los Angeles; the combination of wine tasting, farm dining, and the nearby colonial port city of Ensenada makes it the most culturally rich short trip from San Diego. Mission San Tomas (1791) and the ruins of Mission Santo Domingo (1775) are accessible from the valley for those interested in the Baja mission trail.